Olive Oil and Liver Health

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Olive Oil and Liver Health

A new research study reports that Extra Virgin Olive Oil can protect the liver against the effects of damage from alcohol or oxidative stress.

As part of the study, scientists exposed laboratory rats to a moderately toxic herbicide known to deplete antioxidants and cause oxidative stress, finding that those rats fed on a diet containing the olive oil were partially protected from the resulting liver damage.

Mohamed Hammami from the University of Monastir, Tunisia and King Saud University, Riyadh ,worked with a team of researchers to carry out the experiments.

He said, “Olive oil is an integral ingredient in the Mediterranean diet. There is growing evidence that it may have great health benefits including the reduction in coronary heart disease risk, the prevention of some cancers and the modification of immune and inflammatory responses. Here, we’ve shown that extra virgin olive oil and its extracts protect against oxidative damage of hepatic tissue.”

The researchers separated the subjects into a control group, an olive oil group, and 6 groups that were exposed to the herbicide ‘2,4-Dichlorophenoxyacetic acid’ with or without either whole olive oil, or one of two oil extracts “ the hydrophilic fraction or the lipophilic fraction. All subjects given the herbicide showed signs of significant liver damage.

However, extra virgin olive oil and hydrophilic fraction intake induced a significant increase in antioxidant enzyme activity and a decrease in markers of liver damage.

Speaking about the results, Hammami said, “The hydrophilic fraction of olive oil seems to be the effective one in reducing toxin-induced oxidative stress, indicating that hydrophilic extract may exert a direct antioxidant effect on hepatic cells. However, more detailed studies about the effect of antioxidant compounds separately and/or their interactions are necessary to substantiate these observations.”

The study appears in BioMed Central’s open access journal Nutrition and Metabolism

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